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Lyme Regis is a coastal town in West Dorset, England, situated 25 miles west of Dorchester and 25 miles (40 km) east of Exeter. The town lies in Lyme Bay, on the English Channel coast at the Dorset-Devon border. It is nicknamed "The Pearl of Dorset." In the 13th century it developed into one of the major British ports. The town was home to Admiral Sir George Somers, its one time mayor and parliamentarian, who founded the Somers Isles, better known as Bermuda. Lyme Regis is twinned with St. George's, in that Atlantic archipelago.

The town has a population of 4,406, 45% of whom are retired. Lyme is mentioned in the Domesday Book of 1086. The Royal Charter was granted by King Edward I in 1284, with the addition of 'Regis' to the town's name. This charter was confirmed by Elizabeth I in 1591.

In 1644, during the English Civil War, Parliamentarians here withstood an eight week siege by Royalist forces under Prince Maurice. It was at Lyme Regis that the Duke of Monmouth landed at the start of the Monmouth Rebellion in 1685.

In the early 1960s, the town's railway station was closed, as part of the Beeching Axe. It was rebuilt at Alresford, on the Mid Hants Watercress Railway in Hampshire. The route to Lyme Regis had been notable for being operated by aged Victorian locomotives, one of which is now used on the Bluebell Line in Sussex.

In 2005, as part of the bicentenary re-enactment of the arrival of the news, aboard the Bermuda sloop HMS Pickle, of Admiral Nelson's victory at the Battle of Trafalgar in 1805, the actor playing the part of Trafalgar messenger Lieutenant Lapenotiere was welcomed at Lyme Regis.

Lyme Regis is well-known for "The Cobb", a harbour wall full of character and history. It is an important feature in Jane Austen's novel Persuasion (1818), and in the film The French Lieutenant's Woman, based on the 1969 novel of the same name by local writer John Fowles.

The Cobb was of enormous economic importance to the town and surrounding area, allowing it to develop as both a major port and a ship-building centre from the 13th century onwards. The wall provided both a breakwater to protect the town from storms and an artificial harbour.

Well-sited for trade with France, the port's most prosperous period was from the 16th century until the end of the 18th century and as recently as 1780 it was larger than Liverpool. The town's importance as a port declined in the 19th century because it was unable to handle the increase in ship sizes.

The first written mention of the Cobb is in a 1328 document describing it as having been damaged by storms. The structure was made of oak piles driven into the seabed with boulders stacked between them. The boulders were floated into place tied between empty barrels.

A 1685 account describes it as being made of boulders simply heaped up on each other: "an immense mass of stone, of a shape of a demi-lune, with a bar in the middle of the concave: no one stone that lies there was ever touched with a tool or bedded in any sort of cement, but all the pebbles of the see are piled up, and held by their bearings only, and the surge plays in and out through the interstices of the stone in a wonderful manner."